Experimental Studies on the Efficacy of T1sr and T1/44 Vaccine Strains of Mycoplasma mycoides Subspecies mycoides (Small Colony) against a Field Isolate Causing Contagious Bovine Pleuropneumonia in Kenya - Effect of a Revaccination
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چکیده
Contagious bovine pleuropneumonia (CBPP) is an important disease of cattle in Africa caused by Mycoplasma mycoides subsp. mycoides biotype small colony (MmmSC) and characterized by extensive lesions of pleurisy and pneumonia (13). Among infectious diseases that threaten African cattle, its importance is only second to rinderpest (RP) and, as more and more countries declare being free of RP, CBPP is likely to become the major priority for Veterinary Services in that continent.
منابع مشابه
Complete Genome Sequence of Mycoplasma mycoides subsp. mycoides T1/44, a Vaccine Strain against Contagious Bovine Pleuropneumonia
Mycoplasma mycoidessubsp.mycoidesis the etiologic agent of contagious bovine pleuropneumonia. We report here the complete genome sequence of the strain T1/44, which is widely used as a live vaccine in Africa.
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Specific humoral immune responses in a clinical trial on cattle for vaccines against contagious bovine pleuropneumonia (CBPP) were investigated. The trial included a subunit vaccine consisting of five recombinant putative variable surface proteins of the infectious agent Mycoplasma mycoides subsp. mycoides small colony type (M. mycoides SC) compared to the currently approved attenuated vaccine ...
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The clinical course of infection following endobronchial inoculation of three strains of Mycoplasma mycoides subspecies mycoides small colony (MmmSC), the causative agent of Contagious Bovine Pleuropneumonia (CBPP), was compared in 15 mixed-breed Bos taurus steers. Two of these strains have not previously been investigated under experimental conditions. The cattle were inoculated endobronchiall...
متن کاملCharacterization of strains of Mycoplasma mycoides subsp. mycoides small colony type isolated from recent outbreaks of contagious bovine pleuropneumonia in Botswana and Tanzania: evidence for a new biotype.
Four strains of Mycoplasma mycoides subsp. mycoides small colony type (MmmSC) isolated from recent outbreaks of contagious bovine pleuropneumonia (CBPP) in Africa have been investigated. One Botswanan strain, M375, displayed numerous and significant phenotypic differences from both contemporary field isolates and older field and vaccine strains (African, Australian, and European strains dating ...
متن کاملAssessing the in vitro effectiveness of antimicrobials against Mycoplasma mycoides subsp. mycoides small-colony type to reduce contagious bovine pleuropneumonia infection.
In vitro minimum inhibitory concentrations were determined for 21 antimicrobials against 41 isolates of Mycoplasma mycoides subsp. mycoides small-colony type, the cause of contagious bovine pleuropneumonia. Of the antimicrobials used most widely in Africa, oxytetracycline and tilmicosin were effective, while the isolates were resistant to tylosin. These results provide a baseline for monitoring...
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تاریخ انتشار 2015